This report provides explanations of the contribution that your genetic profile provides by influencing your health in the following important areas:
What tests are being performed? Once we receive your swab sample, we will use special molecular techniques to amplify your Deoxyribonucleic acid (DNA) for analysis. In this process, called the Polymerase Chain Reaction (PCR), copies of regions of your genes will be amplified many times over, so that we can generate sufficient quantities to analyze your genetic material. We will then identify unique DNA sequences in some of your genes. Certain changes (polymorphisms) in these genes have been studied in detail, and evidence has emerged that correlates these polymorphisms with an individual’s weight management and response to diet and exercise intervention. Having identified the presence or absence of these polymorphisms, we are able to qualitatively assess particular areas of intervention for improved weight management related to the specific genes.
What can our genes tell us? Depending on your unique genetic profile, we will be able to assess if your body is able to mobilize fat stores for energy-efficient and if you are at a greater risk of obesity and elevated insulin levels with carbohydrate (CHO) intake. With this profile, decreasing the intake of CHO has been shown to reduce insulin levels and is beneficial in weight management.
We will also be able to access if your genetic profile is associated with increased obesity risk, especially when dietary saturated fat and omega-6 fatty acids intake is high. If this is part of your personalized profile, we will explain how to manage inflammation by emphasizing dietary intake of omega 3 fatty acids and to monitor saturated fat intake.
Individuals show different genetic responses to exercise as well. Within your genetic result set, we may recommend higher levels of vigorous physical activity, or if moderate exercise works best for you. We will provide you with recommend amounts of weekly exercise, specific to your genetic results, for maximizing your chances of weight loss.
While devising your personalized diet plan, we consider four genetically-based diet and lifestyle factors: exercise, obesity risk, sensitivity to carbohydrates and sensitivity to saturated fats. A brief explanation of these lifestyle factors is given below:
Your best possible DIET PLAN is based on the contribution of weight management genetic variables, and with your personalized results we will customize a weight loss program best suited to your needs following one of three diets:
The Mediterranean food patterns are typical of Crete, Greece and Southern Italy in the early 1960s. The term is closely tied to traditional areas of olive cultivation in the Mediterranean region more than 30 years ago and not to the urbanized diet eaten in those countries today. Several studies have established the health benefits of the Mediterranean diet in reducing the risk of metabolic syndrome, type 2 diabetes, cardiovascular diseases, and some neurodegenerative diseases and cancers. In addition, it has been shown to be an extremely effective eating plan for weight loss.
The Diet is Best Described As:
A low-fat diet is often recommended by the AHA, ASDA Healthy Eating guidelines. In general, a low-fat diet is comprised of a fat intake of less than 30% of total energy. However, for the purpose of weight loss, it is recommended that fat should be reduced to 20% of total energy. We recommend a low-fat diet to individuals who have a greater absorption of dietary fat due to genetic variations and individuals who tend to have a slower mobilization of fat from fat cells.
The Diet is Best Described As:
Low carb diets have a positive impact on obesity, serum lipids, impaired glucose metabolism, and hypertension, but it is important to understand what constitutes a low carbohydrate diet. There is no need to completely cut out carbohydrates from the diet; the same positive results can still be achieved with a small intake of carbohydrates as described in the recommendations below. A low carbohydrate diet limits intake to 30-130g of carbohydrate per day, usually starting with the lower level in the first week or two, increasing to 60-70g per day by week three, and eventually maintaining approximately 100-130g per day.
The Diet is Best Described As:
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